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KMID : 1035520170050010037
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Brain Tumor Research and Treatment : BTRT
2017 Volume.5 No. 1 p.37 ~ p.41
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Subependymal Giant Cell Astrocytoma Presenting with Tumoral Bleeding: A Case Report
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Kim Jae-Young
Jung Tae-Young
Lee Kyung-Hwa
Kim Seul-Kee
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Abstract
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We report a rare case of subependymal giant cell astrocytoma (SEGA) associated with tumoral bleeding in a pediatric patient without tuberous sclerosis complex (TSC). A 10-year-old girl presented with a 2-week history of an increasingly aggravating headache. Brain magnetic resonance imaging revealed an approximately 3.6-cm, well-defined, heterogeneously enhancing mass with multistage hemorrhages on the right-sided foramen of Monro. The tumor was completely resected using a transcallosal approach. Intraoperatively, the mass presented as a gray-colored firm tumor associated with acute and subacute hemorrhages. The origin of the mass was identified as the ventricular septum adjacent to the foramen of Monro. A pathological analysis revealed pleomorphic multinucleated eosinophilic tumor cells with abundant cytoplasm. These cells showed positive staining for the glial fibrillary acidic protein and S100 protein. A diagnosis of SEGA was established. The patient recovered without any neurological symptoms. There was no evidence of TSC. The radiological follow-up showed no recurrence for 2 years. This was a case of SEGA with intratumoral hemorrhage, for which a favorable outcome was achieved, without any neurological deficit after tumoral resection.
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KEYWORD
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Hemorrhage, Astrocytoma, Tuberous sclerosis, Surgery
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